Porcine dermatitis and nephropathy syndrome (PDNS) is a disease affecting pigs, characterized by skin lesions and kidney damage. It primarily occurs in growing pigs and is often associated with infections, particularly by porcine circovirus type 2 (PCV2). The condition can lead to significant economic losses in the swine industry due to decreased growth rates and increased mortality. Symptoms of PDNS include red or purple skin lesions, especially on the hindquarters, and signs of kidney dysfunction. Affected pigs may also show signs of fever and lethargy. Early detection and management are crucial to minimize the impact of this syndrome on pig health and farm productivity.