The nonfluent/agrammatic variant is a type of primary progressive aphasia characterized by difficulty in speech production. Individuals often struggle to form complete sentences, leading to short, fragmented speech. They may omit small words, such as "is" or "the," which can make their speech sound telegraphic. This variant primarily affects the left frontal lobe of the brain, impacting areas responsible for language processing. People with this condition may also have challenges with grammar and word retrieval, while their comprehension and ability to recognize familiar objects often remain relatively intact.