The monkeypox virus is a rare viral infection that primarily occurs in central and west Africa. It is similar to smallpox but generally causes milder symptoms. The virus is transmitted to humans through contact with infected animals, such as rodents or monkeys, or through human-to-human contact. Symptoms of monkeypox include fever, rash, and swollen lymph nodes, which can lead to painful lesions on the skin. While the disease is usually self-limiting, it can be severe in some cases. Vaccines developed for smallpox may offer some protection against monkeypox, and public health measures are important for controlling outbreaks.