Macrolides are a class of antibiotics that are commonly used to treat various bacterial infections. They work by inhibiting protein synthesis in bacteria, which helps to stop their growth and reproduction. Macrolides are effective against a range of pathogens, including those that cause respiratory infections, skin infections, and some sexually transmitted diseases. Some well-known examples of macrolides include erythromycin, azithromycin, and clarithromycin. These medications are often preferred for patients who are allergic to penicillin or for those who require an alternative treatment option. Macrolides are generally well-tolerated, but they can have side effects, such as gastrointestinal discomfort and potential interactions with other medications.