Leukotriene receptor antagonists (LTRAs) are a class of medications used primarily to manage asthma and allergic rhinitis. They work by blocking the action of leukotrienes, which are chemicals in the body that cause inflammation, bronchoconstriction, and mucus production. By inhibiting these effects, LTRAs help to reduce airway swelling and improve breathing. Common examples of LTRAs include montelukast and zafirlukast. These medications are typically taken orally and can be used alongside other asthma treatments, such as inhaled corticosteroids, to enhance overall control of symptoms. LTRAs are generally well-tolerated, with few side effects.