Incretins are hormones produced in the gut that help regulate blood sugar levels after eating. They stimulate the pancreas to release more insulin, which helps lower blood sugar. Two main incretins are glucagon-like peptide-1 (GLP-1) and gastric inhibitory peptide (GIP). These hormones also slow down digestion and reduce appetite. Incretins play a crucial role in the body's response to food intake. When you eat, incretins are released into the bloodstream, enhancing insulin secretion in a glucose-dependent manner. This means they help the body manage blood sugar levels more effectively, especially after meals.