The hypodermis, also known as the subcutaneous layer, is the deepest layer of skin located beneath the dermis. It primarily consists of loose connective tissue and fat cells, which help insulate the body and store energy. This layer also contains larger blood vessels and nerves that extend into the upper layers of the skin. In addition to providing insulation and energy storage, the hypodermis plays a crucial role in cushioning the underlying muscles and bones. It helps anchor the skin to these structures while allowing for flexibility and movement. The health of the hypodermis is important for overall skin integrity and function.