Hexokinase II is an enzyme that plays a crucial role in the metabolism of glucose, the primary energy source for cells. It catalyzes the conversion of glucose into glucose-6-phosphate, which is an essential step in the glycolysis pathway. This process helps cells utilize glucose for energy production and storage. This enzyme is predominantly found in tissues with high energy demands, such as muscle and brain cells. Hexokinase II is regulated by the levels of glucose and glucose-6-phosphate, ensuring that energy production is matched to the cell's needs. Its activity is vital for maintaining proper cellular function and energy balance.