A grid framework is a structured layout system used in web design and development to create responsive and organized web pages. It divides the page into rows and columns, allowing designers to place elements like text, images, and buttons in a systematic way. This helps maintain visual consistency and improves user experience across different devices. Grid frameworks, such as Bootstrap and CSS Grid, provide predefined classes and styles that simplify the design process. By using these frameworks, developers can quickly create layouts that adapt to various screen sizes, ensuring that websites look good on both desktops and mobile devices.