Duloxetine is a prescription medication primarily used to treat major depressive disorder and generalized anxiety disorder. It belongs to a class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs), which work by increasing the levels of certain neurotransmitters in the brain to help improve mood and reduce anxiety. In addition to its use for depression and anxiety, duloxetine is also prescribed for chronic pain conditions, such as fibromyalgia and diabetic neuropathy. It is important for patients to follow their healthcare provider's instructions and discuss any potential side effects or interactions with other medications.