Decarboxylases are enzymes that facilitate the removal of a carboxyl group from organic compounds, typically resulting in the release of carbon dioxide (CO2). This process is essential in various biological pathways, including the metabolism of amino acids and the synthesis of neurotransmitters. These enzymes play a crucial role in cellular respiration and the production of energy. For example, the decarboxylation of pyruvate to acetyl-CoA is a key step in the Krebs cycle, which generates energy for the cell. Decarboxylases are vital for maintaining metabolic balance and supporting various physiological functions.