Cytochrome P450 reductase is an essential enzyme found in many organisms, including humans. It plays a crucial role in the metabolism of various substances by transferring electrons to cytochrome P450 enzymes, which are involved in the oxidation of drugs and other compounds. This process is vital for detoxifying harmful substances and synthesizing important biological molecules. The enzyme is located in the endoplasmic reticulum of cells and requires NADPH as a cofactor to function. By facilitating electron transfer, cytochrome P450 reductase helps regulate various biochemical pathways, impacting drug metabolism, hormone synthesis, and the breakdown of environmental toxins.