Cofilin is a protein that plays a crucial role in the regulation of the cytoskeleton, which is the structural framework of cells. It primarily binds to actin, a protein that forms filaments and is essential for various cellular functions, including movement and shape. By severing and depolymerizing actin filaments, cofilin helps to control the dynamics of the cytoskeleton, allowing cells to adapt to their environment. In addition to its role in cell structure, cofilin is involved in several cellular processes, such as cell division, cell migration, and signal transduction. Dysregulation of cofilin activity has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance in maintaining cellular health and function.