Chaperonins are a type of protein that assist in the proper folding of other proteins within cells. They provide a protective environment, ensuring that newly synthesized proteins achieve their correct three-dimensional shapes, which is crucial for their function. Misfolded proteins can lead to various diseases, making chaperonins essential for cellular health. These molecular helpers are typically large, cylindrical structures composed of multiple subunits. They work by encapsulating the target protein, allowing it to fold without interference from other cellular components. Chaperonins are found in all domains of life, including bacteria, archaea, and eukaryotes.