c-Jun
c-Jun is a protein that plays a crucial role in regulating gene expression. It is part of the AP-1 transcription factor complex, which is involved in various cellular processes, including cell growth, differentiation, and response to stress. c-Jun is activated in response to various signals, such as growth factors and cytokines, and can influence the behavior of cells in both normal and disease states.
In addition to its role in normal cellular functions, c-Jun has been implicated in several diseases, including cancer. Overexpression or dysregulation of c-Jun can lead to uncontrolled cell proliferation and survival, contributing to tumor development. Understanding c-Jun and its pathways is essential for developing targeted therapies in cancer treatment.