Anaplastic refers to a type of cell that has lost its normal structure and function, often seen in certain types of cancer. These cells are usually more aggressive and can grow and spread rapidly. For example, anaplastic thyroid cancer is a rare but very serious form of thyroid cancer that can be difficult to treat. In anaplastic cells, the usual characteristics that help cells perform their specific roles are disrupted. This can lead to uncontrolled growth and the formation of tumors. Understanding anaplastic changes is crucial for developing effective treatments for cancers like anaplastic thyroid cancer and improving patient outcomes.