Alpha-synuclein is a small protein found primarily in the brain. It plays a role in the regulation of neurotransmitters, which are chemicals that transmit signals between nerve cells. This protein is important for normal brain function, but its exact role is still being studied. In certain conditions, such as Parkinson's disease, alpha-synuclein can misfold and aggregate, forming clumps known as Lewy bodies. These aggregates are associated with the degeneration of nerve cells, leading to the symptoms of Parkinson's disease, including tremors and difficulty with movement. Understanding alpha-synuclein is crucial for developing potential treatments for these neurodegenerative disorders.