Alpha-oxidation is a biochemical process that occurs in the mitochondria of cells, primarily in the liver. It involves the breakdown of fatty acids, specifically those with branched-chain structures. This process helps convert these fatty acids into smaller molecules that can be further metabolized for energy. During alpha-oxidation, the first step involves the removal of a single carbon atom from the fatty acid chain. This is different from the more common beta-oxidation, which removes two carbon atoms at a time. The end products of alpha-oxidation can then enter other metabolic pathways, contributing to energy production and maintaining cellular function.