Aldehyde dehydrogenase is an enzyme that plays a crucial role in the metabolism of aldehydes, which are organic compounds containing a carbonyl group. This enzyme helps convert aldehydes into carboxylic acids, facilitating the detoxification of harmful substances in the body. It is particularly important in the breakdown of alcohol, as it helps process ethanol into less toxic forms. This enzyme is found in various tissues, including the liver, where it contributes to the body's ability to handle alcohol consumption. Variations in the ALDH2 gene can affect enzyme activity, leading to differences in alcohol tolerance among individuals.