Adrenal disease refers to a group of disorders affecting the adrenal glands, which are small glands located on top of each kidney. These glands produce hormones that regulate various bodily functions, including metabolism, immune response, and stress management. Common types of adrenal disease include Cushing's syndrome, Addison's disease, and adrenal tumors. Symptoms of adrenal disease can vary widely depending on the specific condition. For instance, Cushing's syndrome may cause weight gain and high blood pressure, while Addison's disease can lead to fatigue, weight loss, and low blood pressure. Diagnosis typically involves blood tests, imaging studies, and hormone level assessments.