"X-Men #1," published in 1963, is the debut issue of the iconic comic series created by Stan Lee and Jack Kirby. It introduces a team of superheroes known as the X-Men, who are mutants with extraordinary abilities. The story focuses on their struggle for acceptance in a world that fears and hates them, highlighting themes of prejudice and diversity. The main characters include Professor X, the leader and founder of the X-Men, and his students: Cyclops, Jean Grey, Beast, Iceman, and Angel. They face off against their first adversary, Magneto, who seeks to dominate humanity. This issue set the stage for decades of storytelling in the Marvel Comics universe.