World Down Syndrome Day is observed on March 21 each year to raise awareness about Down syndrome, a genetic condition caused by the presence of an extra copy of chromosome 21. The day aims to promote understanding, acceptance, and inclusion of individuals with Down syndrome in society. The date, 3/21, symbolizes the triplication of the 21st chromosome. Various activities and events take place globally, including educational programs, community gatherings, and social media campaigns, to celebrate the lives and contributions of people with Down syndrome and to advocate for their rights and opportunities.