The term "Whipple" can refer to several things, but it is most commonly associated with the Whipple procedure, a complex surgical operation used to treat pancreatic cancer. This procedure involves the removal of the head of the pancreas, part of the small intestine, the gallbladder, and the bile duct. It is typically performed when cancer is localized and has not spread to other organs. Another notable reference is to Whipple's disease, a rare bacterial infection that affects the gastrointestinal system and can lead to malabsorption. It is caused by the bacterium Tropheryma whipplei and can result in symptoms like weight loss, diarrhea, and abdominal pain. Early diagnosis and treatment with antibiotics are crucial for managing this condition.