Virginia Henderson was an influential American nurse and nursing theorist, known for her work in defining the role of nursing. She developed the Henderson Nursing Theory, which emphasizes the importance of patient independence and the nurse's role in helping patients meet their basic needs. Her contributions have shaped nursing education and practice. Henderson is often referred to as the "first lady of nursing" due to her extensive writings and research. She authored the widely used textbook, Principles and Practice of Nursing, which has educated countless nursing students. Her legacy continues to impact the nursing profession today.