The VDRL test (Venereal Disease Research Laboratory test) is a blood test used to screen for syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. It detects non-specific antibodies that may be present in the blood due to the infection. The test is often used for initial screening, and if positive, further confirmatory tests are required. The VDRL test is simple and quick, typically requiring only a small blood sample. It is important to note that the test can yield false-positive results due to other conditions, such as lupus or pregnancy. Therefore, it is essential to follow up with additional testing for an accurate diagnosis.