Urea Cycle Disorders
Urea Cycle Disorders (UCDs) are genetic conditions that affect the body's ability to remove ammonia, a toxic byproduct of protein metabolism. Normally, the urea cycle converts ammonia into urea, which is then excreted in urine. In individuals with UCDs, a deficiency in one of the enzymes involved in this cycle leads to the accumulation of ammonia in the bloodstream, which can cause serious health issues.
Symptoms of UCDs can include vomiting, confusion, seizures, and in severe cases, coma. Early diagnosis and treatment are crucial to manage these disorders effectively. Treatment options may include dietary changes, medications, and in some cases, liver transplantation to restore normal urea cycle function.