The Uchiha Clan Massacre refers to a tragic event in the Naruto series where the entire Uchiha Clan, a powerful family known for their unique Sharingan abilities, was killed by one of their own, Itachi Uchiha. This massacre was orchestrated under the orders of the Konoha village leadership to prevent a coup d'état that the clan was planning against the village. Itachi, who was a prodigy and a member of the Anbu, carried out the massacre to protect his younger brother, Sasuke Uchiha, and the village. The event deeply affected the storyline, leading to themes of betrayal, revenge, and the complex nature of loyalty within the Naruto universe.