The USS St. Louis is a name used by several ships in the United States Navy, named after the city of St. Louis, Missouri. The most notable among them is the USS St. Louis (CL-49), a Cleveland-class light cruiser commissioned in 1943. It served during World War II, participating in various battles in the Pacific Theater. Another significant vessel is the USS St. Louis (LCS-19), a Freedom-class littoral combat ship commissioned in 2020. This modern ship is designed for operations close to shore and is equipped with advanced technology to perform various missions, including anti-surface and anti-mine warfare.