The USS S-16 was a United States Navy submarine, part of the S-class fleet, launched on March 1, 1919. Designed for coastal defense, it was equipped with torpedoes and had a displacement of about 1,000 tons when submerged. The submarine was primarily used for training and testing purposes during its service. Commissioned in 1922, the USS S-16 served in various roles until it was decommissioned in 1931. It was later sold for scrap in 1934. The S-class submarines, including the USS S-16, played a significant role in the development of submarine technology during the early 20th century.