U.S. Route 68 is a major highway in the United States that stretches approximately 400 miles. It runs from U.S. Route 60 in Kentucky to U.S. Route 50 in Colorado. The route passes through several states, including Ohio, Indiana, and Illinois, providing access to various towns and cities along the way. Established in the 1920s, U.S. Route 68 serves as an important connector for local and regional traffic. It is known for its scenic views and historical significance, making it a popular choice for travelers exploring the heartland of America.