"Twice in a Lifetime" is a 1985 drama film directed by Don McKellar. The story revolves around a man named Joe, who is faced with a midlife crisis and the realization that he has not lived his life to the fullest. He struggles with his relationships and the choices he has made, leading him to seek a second chance at happiness. The film explores themes of love, regret, and the pursuit of dreams. It features a cast that includes Ann-Margret and Peter Falk, who portray characters that influence Joe's journey. The narrative emphasizes the importance of seizing opportunities and making meaningful connections.