"The Lives of the Mayfair Witches" is a novel by Anne Rice that follows the story of a family of witches known as the Mayfair clan. The narrative centers on Rowan Mayfair, a talented neurosurgeon who discovers her supernatural abilities and the dark legacy of her ancestors. As Rowan delves deeper into her family's history, she encounters a powerful spirit named Lasher, who influences her life and choices. The novel explores themes of witchcraft, identity, and the complexities of familial bonds, set against a backdrop of mysticism and intrigue.