"The Great Brain" is a children's novel written by John D. Fitzgerald, published in 1967. The story is set in the early 1900s in the small town of Hollister, Utah and follows the adventures of a young boy named Tom Fitzgerald and his older brother, Joe, who is known for his clever schemes and intelligence. The book explores themes of friendship, family, and the challenges of growing up. Through various escapades, Joe uses his "great brain" to navigate problems, often leading to humorous situations and valuable life lessons for Tom and their friends.