"The Adventure of the Speckled Band" is a short story featuring the famous detective Sherlock Holmes and his friend Dr. John Watson. The story revolves around a young woman named Helen Stoner, who seeks Holmes's help after her sister mysteriously died shortly before her wedding. Helen fears for her own life, as she believes the same fate awaits her. Holmes investigates the case, uncovering clues in the Stoner family's estate. He discovers that the sisters were subjected to the sinister plans of their stepfather, Grimesby Roylott, who used a trained snake to commit murder. Holmes ultimately saves Helen and reveals the truth behind the speckled band.