Systemic Sclerosis, also known as scleroderma, is a chronic autoimmune disease that affects the connective tissues in the body. It leads to the hardening and tightening of the skin and can also impact internal organs, such as the heart, lungs, and kidneys. The exact cause is unknown, but it involves an overproduction of collagen, a protein that provides structure to the skin and organs. Symptoms of Systemic Sclerosis can vary widely among individuals and may include skin changes, joint pain, and digestive issues. There are two main types: limited and diffuse, which differ in the extent of skin involvement and the speed of progression. Early diagnosis and management are essential for improving quality of life.