Structure-Based Drug Discovery
Structure-Based Drug Discovery (SBDD) is a method used in pharmaceutical research to design new medications. It relies on the three-dimensional structure of biological molecules, such as proteins, to identify potential drug candidates. By understanding how these molecules interact, scientists can create compounds that fit precisely into the target site, enhancing their effectiveness.
This approach often utilizes techniques like X-ray crystallography and NMR spectroscopy to visualize the target's structure. Once a suitable binding site is identified, computational tools can help design and optimize new drugs, making SBDD a powerful strategy in modern drug development.