Structure-Based Drug Design
Structure-Based Drug Design (SBDD) is a method used in the development of new medications. It involves analyzing the three-dimensional structure of biological molecules, such as proteins, to identify potential drug targets. By understanding how these molecules interact, researchers can design compounds that fit precisely into the target site, enhancing their effectiveness.
This approach often utilizes techniques like X-ray crystallography or NMR spectroscopy to visualize the target's structure. Once a suitable compound is identified, it can be optimized for better binding and reduced side effects, ultimately leading to the creation of more effective and safer drugs.