Stress-Activated Protein Kinases (SAPKs) are a group of enzymes that play a crucial role in cellular responses to stress. They are activated by various stressors, such as UV radiation, oxidative stress, and inflammatory signals. Once activated, SAPKs help regulate important cellular processes, including apoptosis (programmed cell death) and inflammation. SAPKs are part of larger signaling pathways that help cells adapt to challenging conditions. They can influence gene expression and protein activity, ultimately affecting how cells respond to damage or stress. Understanding SAPKs is important for developing therapies for diseases related to stress responses, such as cancer and neurodegenerative disorders.