The Ste. Genevieve Historic District is located in Ste. Genevieve, Missouri, and is recognized for its well-preserved 18th and 19th-century architecture. This area showcases a unique blend of French colonial and American styles, reflecting the town's rich history as one of the oldest European settlements in the state. Designated as a National Historic Landmark, the district features notable structures such as the Ste. Genevieve Catholic Church and the Bolduc House Museum. Visitors can explore the charming streets and learn about the area's cultural heritage, making it a significant destination for history enthusiasts.