The Staudinger reaction is a chemical reaction that involves the conversion of an azide into an amine. This process typically occurs through the reaction of an azide with a phosphine, resulting in the formation of an intermediate that can be hydrolyzed to yield the amine product. This reaction is valuable in organic synthesis for creating amines from readily available azides. Developed by Hermann Staudinger in the early 20th century, the Staudinger reaction is significant in the field of organic chemistry. It allows chemists to efficiently synthesize amines, which are important building blocks in pharmaceuticals and other chemical compounds.