State Route 40 is a significant highway located in the United States, primarily running through the state of Florida. It stretches approximately 100 miles, connecting various towns and cities, and serves as an important route for both local and through traffic. The highway begins in Crescent City and extends westward to Interstate 75, passing through areas like Palatka and Gainesville. State Route 40 is known for its scenic views, including stretches of natural landscapes and access to recreational areas, making it a popular choice for travelers exploring North Central Florida.