The St. Marks River is a river located in the state of Florida, flowing through Wakulla County. It originates from the St. Marks National Wildlife Refuge and meanders approximately 20 miles before emptying into the Gulf of Mexico. The river is known for its scenic beauty and diverse wildlife, making it a popular spot for outdoor activities like kayaking and fishing. The river's watershed supports various ecosystems, including wetlands and forests, which are home to numerous species of birds, fish, and other wildlife. The St. Marks River is also significant for its historical importance, as it was once a vital transportation route for early settlers and traders in the region.