Sister Mary Joseph was a Roman Catholic nun known for her significant contributions to medicine and healthcare. She was born in 1856 and became a member of the Sisters of St. Joseph. Her work primarily focused on providing care to the sick and poor, particularly in the United States. She is perhaps best known for her association with the Mayo Clinic, where she played a crucial role in establishing the hospital's nursing program. The term "Sister Mary Joseph nodule," referring to a specific type of tumor, was named in her honor, recognizing her impact on medical education and patient care.