Sissy Hankshaw is the fictional protagonist of the novel "Even Cowgirls Get the Blues" by Tom Robbins. She is characterized by her large thumbs, which allow her to hitchhike easily across the United States. Sissy embodies a free-spirited lifestyle, seeking adventure and self-discovery while challenging societal norms. Throughout her journey, Sissy encounters various characters and experiences that shape her understanding of freedom and identity. The novel explores themes of individuality, feminism, and the quest for personal fulfillment, making Sissy a symbol of nonconformity and the pursuit of happiness in a complex world.