Sezary Syndrome is a rare and aggressive form of skin lymphoma, specifically a type of T-cell lymphoma. It is characterized by the presence of abnormal T-cells in the blood, skin, and lymph nodes. Patients often experience symptoms such as red, itchy skin, hair loss, and swollen lymph nodes. Diagnosis typically involves a skin biopsy and blood tests to identify the abnormal cells. Treatment options may include chemotherapy, targeted therapy, and phototherapy, but the condition can be challenging to manage due to its aggressive nature and potential for recurrence.