Server-Side Programming refers to the process of creating software that runs on a web server rather than on the user's device. This type of programming is responsible for managing databases, processing user requests, and generating dynamic content that is sent to the user's browser. Common languages used for server-side programming include PHP, Python, and Ruby. When a user interacts with a website, their actions often trigger server-side scripts that perform tasks like retrieving data or updating information. This allows for a more interactive and personalized experience, as the server can respond to user inputs in real-time, ensuring that the content displayed is relevant and up-to-date.