SLC25A5 is a gene that encodes a protein known as the adenine nucleotide translocator (ANT). This protein is primarily located in the inner membrane of mitochondria, the energy-producing structures in cells. Its main function is to facilitate the exchange of adenosine nucleotides, such as ATP and ADP, between the mitochondria and the cytosol, which is essential for cellular energy metabolism. Mutations or dysfunctions in the SLC25A5 gene can lead to various metabolic disorders, affecting how cells produce and utilize energy. Research on this gene is important for understanding conditions related to mitochondrial dysfunction, which can impact overall health and contribute to diseases like diabetes and neurodegenerative disorders.