S. mansoni, or Schistosoma mansoni, is a parasitic worm that causes schistosomiasis, a disease affecting millions worldwide. It primarily inhabits the blood vessels of the intestines and is transmitted through contact with contaminated freshwater, where its larvae, released by infected snails, penetrate the skin of humans. The life cycle of S. mansoni involves both human and snail hosts. After entering the human body, the larvae mature into adult worms, which can live for years, laying eggs that may cause inflammation and damage to organs. Effective prevention and treatment strategies are essential to control the spread of this disease.