Ras Family
The Ras Family refers to a group of proteins known as Ras proteins, which play a crucial role in cell signaling. These proteins help regulate various cellular processes, including growth, differentiation, and survival. Mutations in Ras genes can lead to uncontrolled cell division, contributing to the development of cancers, such as pancreatic and colorectal cancer.
The main members of the Ras family include K-Ras, N-Ras, and H-Ras. These proteins are part of a larger family of GTPases, which are enzymes that bind and hydrolyze guanosine triphosphate (GTP). Understanding the Ras family is essential for developing targeted therapies in cancer treatment.