The Qualley Sisters are two American actresses, Margaret Qualley and Rainey Qualley, known for their work in film and television. Margaret gained recognition for her roles in series like The Leftovers and films such as Once Upon a Time in Hollywood. Rainey, also an actress, has appeared in various projects and is known for her music career as well. Both sisters come from a creative background; their mother is Andie MacDowell, a well-known actress and model. The Qualley Sisters have carved out their own paths in the entertainment industry while maintaining a close relationship with each other.